News ImmuneRegen NewsImmuneRegen Announces Further Results From Anthrax Treatment StudyAugust 17, 2006 07:00:00 AM ET Hyperion Biotechnology, Inc. and ImmuneRegen Continue Testing the Effects of Viprovex(TM) for Possible Use to Treat the Effects of Anthrax Exposure SCOTTSDALE, Ariz., Aug. 17 /PRNewswire-FirstCall/ -- ImmuneRegen BioSciences, a wholly owned subsidiary of IR BioSciences Holdings, Inc. (OTC Bulletin Board: IRBO), today announced further results from pre-clinical tests of Viprovex(TM) for possible use to treat the effects of pulmonary anthrax infection. ImmuneRegen is collaborating with Hyperion Biotechnology Inc. to perform these tests at Hyperion's research facility located on the United States Air Force School of Aerospace Medicine (USAFSAM) campus in Brooks City-Base, Texas. Initial studies in a well-established mouse model system indicate a potential positive effect in the use of Viprovex® to both prophylactically and therapeutically treat the effects of a near lethal anthrax-exposure. Animals exposed to near lethal doses of anthrax spores were treated with Viprovex® either before anthrax exposure or afterwards and test results indicated a survival rate ranging from 20% to 70% of control animals that otherwise would likely have died. In vitro studies confirm elevation of multiple classes of immunomodulators in response to Viprovex®, and management believes these results add further support to continued efforts towards additional testing of Viprovex®. "The company is optimistic in its development of the compound for this unmet medical need," says a company spokesperson. Studies utilizing a formulation of the same active ingredient, Homspera(TM), in an animal model of lethal radiation exposure, show increased survival and immune system reconstitution, lending credence to the hypothesis that Homspera may be of value in a number of biodefense applications. About Viprovex® Viprovex® is the trade name used in referring to formulations of Homspera for potential indications for treatment of maladies caused by exposure to various chemical and biological agents. Homspera is a generic name used by the Company to describe the synthetic peptide Sar9, Met (O2)11-Substance P. Sar9, Met (O2)11-Substance P is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species. All of the Company's research and development efforts are early, pre-clinical stage and both Homspera and Viprovex® have only undergone exploratory studies to evaluate their biological activity in small animals. About Hyperion Hyperion Biotechnology was founded in 1998 and has active programs in the area of biomarker discovery, wound healing, performance enhancement, infectious disease treatment and other homeland security related topics. These research efforts have been funded by contracts with the Department of Defense (DoD). About ImmuneRegen BioSciences, Inc.a wholly owned subsidiary of IR BioSciences Holdings, Inc., (OTC BB:IRBS.OB - News) is a development-stage biotechnology company focused on the research, development and licensing of Homspera™ and its derivatives. Homspera is an adult stem cell active compound that in study results has been shown to regenerate and strengthen the immune system and enhance wound healing. Viprovex®, a derivative of Homspera, is being developed for potential use against infectious diseases as a stand-alone or combination therapy and as a vaccine adjuvant. To advance its mission, the Scottsdale, Arizona based company has forged numerous study partnerships with industry and academic leaders, including Celgene Cellular Therapeutics, HemoGenix, Lovelace Respiratory Research Institute and Virion Systems. For more information, please visit www.immuneregen.com. Statements about ImmuneRegen's future expectations, including statements about the potential use and scientific results for ImmuneRegen's drug candidates, science and technology, and all other statements in this press release other than historical facts, are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934, and as that term is defined in the Private Securities Litigation Reform Act of 1995. ImmuneRegen intends that such forward-looking statements be subject to the safe harbors created thereby. These future events may not occur as and when expected, if at all, and, together with ImmuneRegen's business, are subject to various risks and uncertainties. ImmuneRegen's actual results could differ materially from expected results as a result of a number of factors, including the uncertainties inherent in research and development collaborations, pre-clinical and clinical trials and product development programs (including, but not limited to the fact that future results or research and development efforts may prove less encouraging than current results or cause side effects not observed in current pre-clinical trials), the evaluation of potential opportunities, the level of corporate expenditures and monies available for further studies, capital market conditions, and others set forth in ImmuneRegen's periodic report on Form 10-Q for the three months ended June 30, 2008 and on Form 10-KSB for the year ended December 31, 2007 as filed with the Securities and Exchange Commission. There are no guarantees that any of ImmuneRegen's proposed products will prove to be commercially successful. ImmuneRegen undertakes no duty to update forward-looking statements. Contact: or
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